Two sample MR report
RPS26_Alveolar Macrophages against UKB-b-18436
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 6 | -0.0466465 | 0.0662267 | 0.5200628 |
| Weighted median | 6 | -0.0442801 | 0.0097010 | 0.0000050 |
| Inverse variance weighted | 6 | -0.0458127 | 0.0076573 | 0.0000000 |
| Simple mode | 6 | -0.0429758 | 0.0135259 | 0.0246123 |
| Weighted mode | 6 | -0.0428240 | 0.0119454 | 0.0157915 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 1.579875 | 4 | 0.8124046 |
| Inverse variance weighted | 1.580035 | 5 | 0.9036530 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0005614 | 0.0442883 | 0.9904937 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0003693 | 1e-07 | TRUE | 0.0702715 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
